CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Interrogating Immnunometabolism in the TME Using a Metabolic Checkpoint

Previously considered distinct disciplines, the fields of immunology and metabolism are converging i...
Jianxin Xie, PhD Apr 17, 2024

Hypoxia and Its Role in Metabolism

Hypoxia, defined as the deficiency of oxygen in the biotic environment, causes cellular stress and a...
Chris Sumner Jun 8, 2022

Metabolism and Disease

Metabolism plays a central role in many diseases including diabetes, cardiovascular disease, obesity...
Chris Sumner Oct 27, 2021

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

How Do I Measure Metabolism?

Several different assays can be used by scientists to measure metabolism in a variety of contexts. T...
Chris Sumner Apr 21, 2021

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

Cellular Pathways to Metabolism

Cellular homeostasis is regulated by the coordinated activity of several key metabolic pathways. The...
Chris Sumner Mar 3, 2021

Introduction to Metabolism

Cellular metabolism encompasses all of the chemical processes that occur within cells to maintain ho...
Chris Sumner Feb 3, 2021

Hypoxia and Cancer – the role of HIF-1α in oxygen sensing, metabolism, and tumorigenesis

Molecular oxygen (O2) is an essential element for metazoan life. Among its many roles, O2 functions ...
Jianxin Xie, PhD Mar 27, 2019

ApoE4 and the Insulin Receptor — It's a Trap!

You might be surprised to learn that diabetes, a metabolic disease, may be linked to the neurodegene...
Richard Cho, PhD Aug 1, 2018

Missing Link: Why Do Insulin-producing Cells in Type 2 Diabetes Fail to Divide?

Type 2 diabetes is a growing epidemic, and is recognized as one of the most serious metabolic diseas...
Neha G Jan 17, 2018

Webinar | Advances in AMPK and Autophagy Signaling

Reuben Shaw, Ph.D Professor, Molecular and Cell Biology Laboratory, Deputy Director, Salk Cancer Cen...
Liana G Dec 20, 2017

Journal Club: TREM2 Opens a Rabbit Hole of Questions for Alzheimer’s Researchers

It's almost time for the 2017 Society for Neuroscience meeting. To get your neurons excited for the ...
Richard Cho, PhD Nov 8, 2017

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