CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Cell Process: What is cell senescence?

Cellular senescence is a state of stable cell cycle arrest under which cells remain metabolically ac...
Tamar A Aug 12, 2020

Cell Process: How is cytotoxicity assessed?

Changes in cellular health in response to exogenous stimuli can provide keen insight into the biolog...
Tamar A Jul 8, 2020

Cell Process: Seven Assays to Detect Apoptosis

Apoptosis is a highly regulated form of programmed cell death that occurs in multicellular organisms...
Tamar A Jul 1, 2020

Cell Process - How is cell proliferation quantified?

The production of new cells through cellular proliferation impacts the development, growth, and main...
Tamar A Apr 22, 2020

Cell Process: What is cell viability and how can it be measured?

The health of cells in culture is critical to the success of your experiments. Have you ever been ex...
Tamar A Apr 15, 2020

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan K Mar 25, 2020

Tools to Help Researchers Fight COVID-19

In order to quickly defeat SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2，previously na...
Maxine M Feb 26, 2020

The Guide to the Hallmarks of Cancer Research Targets

If you haven’t heard already, it’s CST’s 20th anniversary. Woohoo! You could say this year is kind o...
Chris Sumner Oct 9, 2019

Hallmarks of Cancer: Genome Instability and Mutation

Not all cancer cells are equal, they evolve in response to selective pressure driven by accumulation...
Chris Sumner Aug 28, 2019

Hallmarks of Cancer: Tumor Promoting Inflammation

Cancer cells hijack inflammatory mechanisms to promote their own growth and survival. During a norma...
Chris Sumner Aug 21, 2019

Webinar | Linking Senescence with DNA Damage and the Cell Cycle

Gain insight into the processes by which senescent cells contribute to tumor suppression and age-rel...
Chris Sumner Aug 14, 2019

Hallmarks of Cancer: Activation Invasion and Metastasis

Cancer cells invade local tissue and spread to distant sites via two distinct, but similar processes...
Chris Sumner Jul 17, 2019

Hallmarks of Cancer: Avoiding Immune Destruction

Some cancer cells adapt mechanisms to evade detection and destruction by the host's immune system. O...
Chris Sumner Jun 12, 2019

Who am I: Can a cellular identity crisis lead to cancer progression?

The process of epithelial-mesenchymal transition (EMT), whereby differentiated epithelial cells tran...
Antony Wood, PhD May 29, 2019

What is Senescence?

Cellular senescence is defined by permanent cell cycle arrest. Senescent cells accumulate with age a...
Susan K May 22, 2019

Hallmarks of Cancer: Evading Growth Suppressors

Cancer cells resist inhibitory signals that might otherwise stop their growth. The major pathways in...
Chris Sumner May 1, 2019

Hallmarks of Cancer: Enabling Replicative Immortality

Cancer cells can revert to a pre-differentiated, stem-cell-like phenotype, allowing uninhibited cell...
Chris Sumner Apr 17, 2019

Hallmarks of Cancer: Sustaining Proliferative Signaling

Cancer cells stimulate their own growth, which means they become self-sufficient in growth signals a...
Chris Sumner Apr 3, 2019

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